I love, love, LOVE red handbags! I love the color red but have difficulty wearing it, so I try to console myself with small doses of bright red accessories. The red handbag is ideal, and especially adds a small, bold hit of color to neutral business attire. I love how it can be paired with black, brown and gray--it's so versatile. I recently bought this subtle, business-appropriate handbag and am just in love with it:
http://www.zappos.com/hobo-international-luisa
But I find I love carrying it with casual weekend outfits too.