Um, everywhere we went at our last gathering--oh wait, you weren't there :p
honestly, if you just get off at broadway-Lafayette on the 6 train and cross Houston street (where SOuth of HOuston street officially begin), you will have the world as your oyster. Off the top of my head: zara, esprit, two h&ms, mango, banana republic, Ann Taylor, uniqlo, topshop...ok, some of these are not April stores but they're what I know best...
If you deviate from broadway a bit, there is an Anne Fontaine boutique and also Karen Millen and lots of fancier places where they have doormen and wrap your purchases in tissue paper. There are also Tory Burch and Nanette Lepore boutiques in the vicinity. I recommend strolling through Nolita for more privately owned goods and services. Including that store I wanted to race to with Angie and Laura--Frocks.
Realistically though, all you have to do is get off the train or cab and walk around. It's basically a big shopping mall.
Have fun!
