Fall and winter aren't so bad, and I don't seem to have spot-specific issues like excessive underarm sweating. However, I react very, very poorly to hot weather. So much so that when we visit a hot climate on vacation, I am pretty sure that observers think there is something the matter with me because I sweat so much. My face is the worst, and one cannot exactly put anti-perspirant on one's face! But "oil-free" sunscreens and facial products don't do a thing for me because my skin is not only sweaty, but oily as well. I suppose it helps as far as aging and wrinkling goes, but it is miserable.
As for clothing, I launder the layer closest to my skin after each wear, so that means that I wear a freshly laundered bra, underwear (of course), socks, cami or t-shirt and tights daily. In the summertime, I rarely wear anything more than once between washings, but in winter I can usually wear pants twice and jackets or cardigans several times.