Haven't heard of the game, but I looked up the site (where they switch out black cards and white cards, showing the possibilities), and it remind me of Bubble Talk for adults. DH and the kids and I play Bubble Talk, and sometimes DH and I are laughing hysterically over something the kids don't get at all. Granted, Bubble Talk is more suggestions of impropriety as opposed to stating it in black and white, but Cards Against Humanity looks like a fun game for adults!
Oh, and I've heard that anti-chafing gel can be used as primer (though I haven't tried it).