Hmmm. I am a bit stumped on an answer to this - for myself I say neither. I do not like desaturated color much if it means mauve, dusty sage or seafoam green, military or washed out chambray blue, or very faded blacks.
However, I don’t much go for clear brights like primary red, yellow, blue, cobalt or peacock blue, hot or bubblegum pink, bright orange or salmon. If those are dopamine, then I’m not for ‘em.
An all neutral collection is also not in my closet or future.
My favorites are darker, richer and low contrast outfits, with forest or pine green, burgundy, navy, teal, rust, darker golds, some darker purples, dark to medium grays, and nix the cream, white, or palest grays unless only a small portion of outfit or pattern.
So rather than either soft and desaturated or colorful dopamine, I have to claim darker, richer colors and low contrast to be my preferred palette.