Most of the restaurants in the South End are excellent - difficult to make a bad choice. The trouble is making one!
Down near the cyclorama and the BCA on Tremont street there are a lot of great restaurants. Beehive, Aquitaine, Stephanie's (same as the one on Newbury we had one of the past YLF meet ups at), B&G Oysters, Addis Red Sea (Ethiopean), Mela (upscale/gourmet indian), to name my favorites.
If you are down that way, be sure to check out the Mills Gallery before dinner/before it closes -- it's small, but is one of my favorite galleries in the whole city. (And if you do go, take a peek in the bathroom because often but not always the exhibit extends into there, too!)
It's right next to Beehive, which is fun restaurant/bar with live entertainment (jazz). If you go to Beehive, here's a fun factoid: the area where the band plays used to be a bizarre little alternative theater... and DH and I had one of our first dates there!
Between Beehive and the BCA theater is the Cyclorama. If it is open to the public, GO IN and check it out. The cyclorama is an amazing piece of Boston architectural history. Not a lot of people even know it exists.
Here is the calendar for BCA, Cyclorama, and Mills Gallery:
http://www.bcaonline.org/calen.....vents.html
Advise if you want to see any of the shows, get your tickets now.
Walk up Tremont towards the SoWa district and there's Tremont 647 which is one of my favorites (I even bought a copy of the chef's signed cookbook, and I don't really cook, ha).
I agree with Mochi, the SoWa first fridays are a lot of fun! There are the professional galleries with store fronts, then there are the artist studios in the buildings - you can traipse through these for hours on end and never hit them all.
Mochi - your friends' art looks familiar! I have probably walked through that gallery! Also I think I have eaten at Coppa. Is it across from Orinoco? DH and I were once driving around exploring and discovered a new restaurant in that area that was awesome, a hidden gem, but we've since tried to find it again and have had no luck. I am wondering if it was Coppa. We are always trying new restaurants so I will be interested in your recommendations -- in south end and beyond.