Wallet
Mobile Phone (I do keep this in my pocket sometimes)
iPod
Camera
Keys
Eye Drops
Mints
Red Swiss Army knife that my husband gave me
Comb
Waterbottle
Sunblock
Work Badge/Bus pass
2 prs Sunglasses (prescription and non for contact days)
Pen
Small pouch with powder, blotting paper, carmex, allergy med, headache med)
Inhaler
Change purse with quarters for parking
Case for glasses and stuff I need to take my contacts out if hayfever overcomes me
Handkerchief
I often also have a scarf of some shape/color in or on my bag
Bobby pins/hair clips (growing out bangs)

Wallet
Mobile phone
Tissues
Hairbrush (even though I can't brush my curls or they'll go frizzy)
Small make up bag with tampons, compact, mascara, lipbalm
Planner
Pantyhose (I have a fear of getting runs lol)
Bobby pins/hairties
Keys
Drink bottle
Museli bar and fruit pack
Ipod
As you can tell I'm the big bag type as well.

Lip balm
iPad
Blackberry
Billfold
Coin Purse
Granola Bar

That's it

I try to keep it simple:

wallet
keys with swiss army knife keychain
sunglasses in their case
dr. bronner's lip balm
3 pens

Many days it also has my laptop (in its case) in there too.