Things are looking bad for both of them, unfortunately.
The little boy's counts haven't been coming up as fast as they did the last time he underwent treatment, so that's a concern. They are almost certainly looking at a bone marrow transplant, with his younger brother being the donor, as he is a match. This situation bothers me a lot, as these are both rather young children (ages 11 and 9).
My brother-in-law had an appointment yesterday, and the news is that his lymphoma appears to be the type that is difficult to treat and extremely likely to return. He still has to go through a pet scan and a bone marrow biopsy before they can come up with a treatment plan. My husband has a business trip coming up that is only about 3 hours away from where they live, so he is going to drive over and pay them a visit. We will also be visiting them for Christmas, as we had originally planned to do.